WDR97

Across TCGA patient cohorts, WDR97 mutation is significantly associated with the RNA expression of many other genes, with 1,629 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR97-associated genes across cancer lineages are IGHV3OR16-8, LINC02550, and RN7SL840P. Each is linked with WDR97 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR97-to-partner and partner-to-WDR97 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHV3OR16-8 grouped by WDR97-low versus WDR97-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR97→partner) and Y-score (partner→WDR97) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGHV3OR16-8 →	+0.513	+2.184	.003	<.001	3	1
UCEC	LINC02550 →	-0.419	-2.991	.006	.001	3	1
UCEC	RN7SL840P →	+0.192	+1.606	.004	.005	3	1
UCEC	CWC25 →	+0.336	+3.053	.004	<.001	3	1
UCEC	LINC02348 →	+0.235	+1.492	.004	.006	3	1
UCEC	ZNHIT3 →	+0.405	+2.223	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,629 associations by consensus.

IGHV3OR16-8 by WDR97 expression — UCEC

Explore this box plot interactively →