WDR97

Across TCGA pan-cancer cohorts, WDR97 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated WDR97 data layer compared with 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher WDR97 RNA is associated with better overall survival. In most high-consensus cancer types, elevated WDR97 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

HNSC, KIRC, and UVM are the cancer types where WDR97 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	0.804	0.686	<.001	93	view →
KIRC	OS	Median	All	0.484	0.727	<.001	86	view →
UVM	DFS	Tertile	III,IV	0.191	0.858	<.001	75	view →
BLCA	OS	Tertile	II,III,IV	0.708	0.556	.003	60	view →
STAD	OS	Quartile	II,III,IV	0.675	0.299	.002	33	view →
PAAD	DFS	Median	All	0.385	0.176	.002	32	view →
COAD	DFS	Median	IV	0.302	0.646	.004	27	view →
SKCM	OS	Median	III,IV	0.572	0.263	.004	25	view →
LIHC	OS	Tertile	II,III,IV	0.286	0.488	.010	18	view →
PRAD	DFS	Median	All	0.823	0.937	<.001	18	view →
THYM	OS	Quartile	II,III,IV	1.000	0.605	.009	16	view →
MESO	DFS	Quartile	IV	0.208	0.797	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

WDR97–HNSC (OS)

Open the HNSC breakdown →