WDR97

Across TCGA cell cohorts, WDR97 mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR97-associated genes across cancer lineages are TCP11X2, KRTAP4-8, and PIGY. Each is linked with WDR97 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR97-to-partner and partner-to-WDR97 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TCP11X2 grouped by WDR97-low versus WDR97-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR97→partner) and Y-score (partner→WDR97) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TCP11X2 →	+0.132	+4.060	<.001	.003	3	2
SKIN	KRTAP4-8 →	+0.759	+2.882	<.001	.005	3	2
SKIN	PIGY →	+1.746	+2.657	.004	.007	3	2
URINARY_TRACT	HTN1 →	+0.131	+3.459	.009	.002	3	1
URINARY_TRACT	CHRDL2 →	+0.103	+3.386	<.001	.008	3	1
OESOPHAGUS	IL17F →	+0.038	+3.836	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

TCP11X2 by WDR97 expression — BLOOD_Leukemia

Explore this box plot interactively →