PIGY

associated omics data
phosphatidylinositol glycan anchor biosynthesis class YGenealiases: HPMRS6 · PIG-Y

Q-omics provides the consensus-scored PIGY profile across patient tissues and cancer cell-line models. PIGY expression is associated with patient survival in 1 of 34 cancer types, with the highest sampling consensus in SCLC. Additionally, PIGY RNA expression shows 972 significant gene co-expression associations, with the highest sampling consensus in SCLC. Together, these results highlight SCLC as cancer lineages where PIGY shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes PIGY survival associations across molecular data types. PIGY RNA expression shows survival associations in the most cancer types (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
PIGY data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier1SCLC (19)view →
This table ranks reproducible PIGY RNA expression–survival associations across cancer types. High PIGY expression shows unfavorable associations in SCLC. The SCLC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .008). Together, the overview and detailed table identify SCLC as the clearest survival context for PIGY RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SCLCDFSMedianAll0.5080.723.00819view →
Pink = unfavorable, green = favorable. all 1 lineages →

PIGY-SCLC (DFS)

Kaplan–Meier survival curve for PIGY RNA expression in SCLC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with PIGY in patient tissues and cancer cell lines. In patient samples, PIGY shows the broadest associations at the RNA and protein expression levels, with SCLC recurring as the lineage with the largest associated feature set. In cancer cell lines, PIGY RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LIVER, while CRISPR and shRNA rows add functional-dependency signals in SKIN.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
RNA972SCLC (972)view →
Function (RNA)357SCLC (357)view →
Mutation
RNA1UCEC (1)view →
Associated data typeStrength (# associated data)Lineage of highest associated data
CRISPR
CRISPR1,867LIVER (191)view →
RNA1,505LIVER (236)view →
RNA
RNA6,081SKIN (3253)view →
Function (RNA)2,337SKIN (787)view →