PIGY

Across TCGA patient cohorts, PIGY mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIGY-associated genes across cancer lineages are RNA5SP376. Each is linked with PIGY in more than 1 cancer types. Because this analysis shows association rather than direction, both PIGY-to-partner and partner-to-PIGY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP376 grouped by PIGY-low versus PIGY-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGY→partner) and Y-score (partner→PIGY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP376 →	+0.556	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

RNA5SP376 by PIGY expression — UCEC

Explore this box plot interactively →