PIGY

Across TCGA cell cohorts, PIGY RNA expression is significantly associated with the go_rna of many other GO terms, with 2,337 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PIGY-associated GO terms across cancer lineages are Transcription pausing by RNA polymerase II, Regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with PIGY in more than 9 cancer types. Because this analysis shows association rather than direction, both PIGY-to-partner and partner-to-PIGY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription pausing by RNA polymerase II grouped by PIGY-low versus PIGY-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGY→partner) and Y-score (partner→PIGY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Transcription pausing by RNA polymerase II →	-0.140	-1.134	<.001	<.001	3	10
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	-0.149	-2.549	<.001	<.001	3	9
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	-0.161	-2.709	<.001	<.001	3	9
BONE	Pre-mRNA catabolic process →	-0.159	-1.921	.003	.004	3	9
LARGE_INTESTINE	Geranyl diphosphate metabolic process →	+0.104	+0.896	<.001	.002	3	9
BONE	DNA replication proofreading →	-0.177	-2.068	<.001	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,337 associations by consensus.

Transcription pausing by RNA polymerase II by PIGY expression — BLOOD_Lymphoma

Explore this box plot interactively →