WDR90

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, WDR90 protein abundance is significantly associated with the RNA expression of many other genes, with 4,018 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible WDR90-associated genes across cancer lineages are RAB36, SAMD15, and CCDC113. Each is linked with WDR90 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR90-to-partner and partner-to-WDR90 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR90 versus RAB36 in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR90→partner) and Y-score (partner→WDR90) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARAB36 →+0.984+0.557.002.00332
UCECSAMD15 →+1.318+0.615<.001<.00132
UCECCCDC113 →+1.205+0.488<.001.00132
UCECCFAP69 →+0.942+0.628<.001<.00132
BRCASPATA6L →+0.799+0.603.002.00132
UCECCEP126 →+1.018+0.540<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,018 associations by consensus.

WDR90 vs RAB36 — BRCA

Per-sample scatter of WDR90 vs RAB36 in BRCA (Pearson r = 0.39).

Explore this scatter interactively →

Exploration