WDR86

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, WDR86 mutation is significantly associated with the RNA expression of many other genes, with 118 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR86-associated genes across cancer lineages are RN7SKP135, OR14A2, and CDK8P1. Each is linked with WDR86 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR86-to-partner and partner-to-WDR86 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR86→partner) and Y-score (partner→WDR86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRN7SKP135 →+0.189+7.687<.001<.00133
SKCMOR14A2 →+0.017+5.225<.001.00132
COADCDK8P1 →+0.194+3.441.008.00332
COADLIF-AS1 →+0.268+3.580.004.00932
UCECRNU6-965P →+0.444+5.253<.001.00132
SKCMRNA5SP105 →+0.247+4.634<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 118 associations by consensus.

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