WDR76

Across TCGA cell cohorts, WDR76 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,353 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WDR76-associated GO terms across cancer lineages are DNA damage tolerance, Spindle elongation, and Meiotic cell cycle. Each is linked with WDR76 in more than 19 cancer types. Because this analysis shows association rather than direction, both WDR76-to-partner and partner-to-WDR76 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA damage tolerance grouped by WDR76-low versus WDR76-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR76→partner) and Y-score (partner→WDR76) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA damage tolerance →	+0.104	+1.467	<.001	<.001	3	20
BLOOD_Myeloma	Spindle elongation →	+0.225	+1.230	.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Meiotic cell cycle →	+0.102	+1.316	<.001	<.001	3	19
OESOPHAGUS	Negative regulation of chromosome segregation →	+0.206	+1.598	<.001	.002	3	19
UPPER_AERODIGESTIVE_TRACT	Immunoglobulin heavy chain V-D-J recombination →	+0.234	+1.622	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic sister chromatid separation →	+0.161	+1.698	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,353 associations by consensus.

DNA damage tolerance by WDR76 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →