WDR76

Across TCGA pan-cancer cohorts, WDR76 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated WDR76 data layer compared with 6 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher WDR76 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated WDR76 expression acts as an unfavorable survival marker, although some lineages such as UCS and READ show a favorable association.

KICH, MESO, and KIRP are the cancer types where WDR76 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Median	All	0.725	1.000	<.001	104	view →
MESO	OS	Tertile	All	0.338	0.707	<.001	93	view →
KIRP	DFS	Tertile	All	0.736	0.916	<.001	93	view →
ACC	OS	Quartile	All	0.301	0.795	<.001	73	view →
LIHC	DFS	Median	All	0.445	0.636	<.001	67	view →
PAAD	OS	Tertile	All	0.457	0.789	<.001	57	view →
LGG	DFS	Median	All	0.656	0.816	<.001	53	view →
LUAD	OS	Median	All	0.761	0.862	<.001	43	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
READ	DFS	Quartile	All	0.775	0.253	.005	23	view →
THYM	OS	Median	All	0.960	0.733	.002	21	view →
BLCA	OS	Median	II,III,IV	0.668	0.766	.010	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

WDR76–KICH (OS)

Open the KICH breakdown →