WDR74

Across TCGA cell cohorts, WDR74 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,843 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WDR74-associated GO terms across cancer lineages are Ribosome biogenesis, Ribosomal large subunit biogenesis, and Ribosomal small subunit biogenesis. Each is linked with WDR74 in more than 16 cancer types. Because this analysis shows association rather than direction, both WDR74-to-partner and partner-to-WDR74 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosome biogenesis grouped by WDR74-low versus WDR74-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR74→partner) and Y-score (partner→WDR74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Ribosome biogenesis →	+0.152	+1.279	<.001	<.001	3	17
BONE	Ribosomal large subunit biogenesis →	+0.138	+0.951	<.001	<.001	3	17
BONE	Ribosomal small subunit biogenesis →	+0.141	+1.185	<.001	<.001	3	17
BONE	rRNA processing →	+0.165	+1.182	<.001	<.001	3	17
BONE	rRNA metabolic process →	+0.132	+0.982	<.001	<.001	3	16
BREAST	rRNA pseudouridine synthesis →	+0.109	+0.687	.001	.006	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,843 associations by consensus.

Ribosome biogenesis by WDR74 expression — BONE

Explore this box plot interactively →