WDR73

Across TCGA patient cohorts, WDR73 mutation is significantly associated with the RNA expression of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR73-associated genes across cancer lineages are USP9YP3, RN7SL50P, and OR4D1. Each is linked with WDR73 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR73-to-partner and partner-to-WDR73 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP9YP3 grouped by WDR73-low versus WDR73-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR73→partner) and Y-score (partner→WDR73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	USP9YP3 →	+0.195	+5.685	<.001	.003	3	2
BLCA	RN7SL50P →	+0.164	+5.038	.009	.009	3	2
BLCA	OR4D1 →	+0.048	+5.251	.002	.006	3	1
BLCA	RNU6-799P →	+0.407	+4.973	<.001	.009	3	1
BLCA	RNA5SP48 →	+0.287	+5.497	<.001	.004	3	1
BLCA	RNU6-1318P →	+0.337	+5.588	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

USP9YP3 by WDR73 expression — BLCA

Explore this box plot interactively →