WDR70

Across TCGA pan-cancer cohorts, WDR70 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated WDR70 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher WDR70 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated WDR70 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

UCEC, LSCC, and CCRCC are the cancer types where WDR70 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.850	0.969	.019	8	view →
LSCC	DFS	Median	II,III,IV	0.858	0.703	.049	2	view →
CCRCC	OS	Median	All	0.783	1.000	.030	1	view →
LUAD	OS	Median	All	0.973	0.911	.023	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

WDR70–UCEC (OS)

Open the UCEC breakdown →