WDR70

Across TCGA patient cohorts, WDR70 protein abundance is significantly associated with the RNA expression of many other genes, with 11,758 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR70-associated genes across cancer lineages are C5orf34, RAD1, and NUP155. Each is linked with WDR70 in more than 8 cancer types. Because this analysis shows association rather than direction, both WDR70-to-partner and partner-to-WDR70 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR70 versus C5orf34 in LSCC, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR70→partner) and Y-score (partner→WDR70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	C5orf34 →	+0.773	+0.442	<.001	<.001	3	9
LSCC	RAD1 →	+0.693	+0.463	<.001	<.001	3	8
LSCC	NUP155 →	+0.823	+0.497	<.001	<.001	3	8
LSCC	ZNF131 →	+0.680	+0.455	<.001	<.001	3	8
LSCC	BRIX1 →	+0.742	+0.442	<.001	<.001	3	7
LUAD	GPR89A →	+0.400	+0.227	.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,758 associations by consensus.

WDR70 vs C5orf34 — LSCC

Explore this scatter interactively →