WDR70

Across TCGA cell cohorts, WDR70 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,784 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible WDR70-associated GO terms across cancer lineages are Protein localization to nuclear inner membrane, Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery, and Cellular response to rapamycin. Each is linked with WDR70 in more than 17 cancer types. Because this analysis shows association rather than direction, both WDR70-to-partner and partner-to-WDR70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to nuclear inner membrane grouped by WDR70-low versus WDR70-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR70→partner) and Y-score (partner→WDR70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein localization to nuclear inner membrane →	+0.192	+0.682	<.001	<.001	3	18
OESOPHAGUS	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.164	+0.848	<.001	<.001	3	14
OESOPHAGUS	Cellular response to rapamycin →	+0.157	+0.726	.002	.002	3	13
STOMACH	Meiotic recombination checkpoint signaling →	+0.239	+0.738	<.001	<.001	2	14
STOMACH	Establishment of mitotic sister chromatid cohesion →	+0.131	+0.800	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Replication-born double-strand break repair via sister chromatid exchange →	+0.194	+0.863	<.001	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,784 associations by consensus.

Protein localization to nuclear inner membrane by WDR70 expression — STOMACH

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