WDR7-OT1

Across TCGA patient cohorts, WDR7-OT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,436 significant associations in total. STAD shows the largest number of these associations.

The most reproducible WDR7-OT1-associated GO terms across cancer lineages are Centrosome duplication, Regulation of chromatin organization, and Positive regulation of DNA metabolic process. Each is linked with WDR7-OT1 in more than 14 cancer types. Because this analysis shows association rather than direction, both WDR7-OT1-to-partner and partner-to-WDR7-OT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centrosome duplication grouped by WDR7-OT1-low versus WDR7-OT1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR7-OT1→partner) and Y-score (partner→WDR7-OT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Centrosome duplication →	+0.068	+0.030	<.001	<.001	3	15
STAD	Regulation of chromatin organization →	+0.067	+0.026	<.001	<.001	3	14
STAD	Positive regulation of DNA metabolic process →	+0.067	+0.028	<.001	<.001	3	14
STAD	Regulation of DNA repair →	+0.063	+0.046	<.001	<.001	3	14
STAD	Cytokinesis →	+0.069	+0.028	<.001	<.001	3	14
STAD	Mitotic DNA integrity checkpoint signaling →	+0.063	+0.029	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,436 associations by consensus.

Centrosome duplication by WDR7-OT1 expression — STAD

Explore this box plot interactively →