WDR7-OT1

Across TCGA pan-cancer cohorts, WDR7-OT1 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated WDR7-OT1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher WDR7-OT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated WDR7-OT1 expression acts as an unfavorable survival marker, although some lineages such as UCS and LUAD show a favorable association.

KIRC, DLBC, and THYM are the cancer types where WDR7-OT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.559	0.714	.012	96	view →
DLBC	OS	Tertile	II,III,IV	0.115	0.839	<.001	72	view →
THYM	DFS	Tertile	III,IV	0.143	0.813	<.001	57	view →
STAD	DFS	Tertile	All	0.194	0.555	.029	36	view →
LGG	DFS	Tertile	All	0.601	0.769	<.001	36	view →
UCS	OS	Tertile	All	0.867	0.518	.042	24	view →
LUAD	DFS	Tertile	IV	0.570	0.523	.019	12	view →
SKCM	OS	Tertile	II,III,IV	0.164	0.407	.009	9	view →
MESO	DFS	Tertile	All	0.154	0.370	.032	9	view →
BRCA	DFS	Tertile	III,IV	0.964	0.866	.044	6	view →
PRAD	DFS	Tertile	All	0.682	0.823	.049	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

WDR7-OT1–KIRC (OS)

Open the KIRC breakdown →