WDR47

Across TCGA patient cohorts, WDR47 mutation is significantly associated with the RNA expression of many other genes, with 3,350 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR47-associated genes across cancer lineages are HSFY4P, MIR4494, and RN7SL134P. Each is linked with WDR47 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR47-to-partner and partner-to-WDR47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSFY4P grouped by WDR47-low versus WDR47-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR47→partner) and Y-score (partner→WDR47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	HSFY4P →	+0.065	+6.681	<.001	<.001	3	2
READ	MIR4494 →	+0.468	+5.219	<.001	.006	3	2
UCEC	RN7SL134P →	+0.089	+2.397	.001	<.001	3	2
BRCA	SNORD116-23 →	+0.375	+3.924	.007	.006	3	2
BRCA	RPS24P21 →	+0.150	+4.065	.001	.005	3	2
LIHC	SPACA5 →	+0.071	+5.108	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,350 associations by consensus.

HSFY4P by WDR47 expression — READ

Explore this box plot interactively →