Q-omics provides the consensus-scored HSFY4P profile across patient tissues and cancer cell-line models. HSFY4P expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in PCPG. Additionally, HSFY4P RNA expression shows 5,410 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight PCPG, and STAD as cancer lineages where HSFY4P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes HSFY4P survival associations across molecular data types. HSFY4P RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

HSFY4P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	PCPG (36)	view →

This table ranks reproducible HSFY4P RNA expression–survival associations across cancer types. High HSFY4P expression shows unfavorable associations in PCPG, THCA, SKCM, HNSC, READ and STAD. The PCPG Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify PCPG as the clearest survival context for HSFY4P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PCPG	OS	Tertile	All	0.010	0.946	<.001	36	view →
THCA	OS	Tertile	All	0.255	0.954	<.001	30	view →
SKCM	DFS	Tertile	IV	0.040	0.454	.028	27	view →
HNSC	DFS	Tertile	IV	0.050	0.570	<.001	27	view →
READ	OS	Tertile	III,IV	0.328	0.751	.003	18	view →
STAD	OS	Tertile	All	0.571	0.729	.033	9	view →

Pink = unfavorable, green = favorable. all 6 lineages →

HSFY4P-PCPG (OS)

Kaplan–Meier survival curve for HSFY4P RNA expression in PCPG: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with HSFY4P in patient tissues and cancer cell lines. In patient samples, HSFY4P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,410	STAD (5119)	view →
RNA	2,735	KIRP (790)	view →