WDR45BP1

Across TCGA pan-cancer cohorts, WDR45BP1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated WDR45BP1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher WDR45BP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated WDR45BP1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and BRCA show a favorable association.

KICH, SKCM, and BRCA are the cancer types where WDR45BP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.689	0.975	.001	43	view →
SKCM	DFS	Median	All	0.667	0.552	.010	27	view →
BRCA	OS	Median	IV	0.945	0.513	.001	26	view →
MESO	DFS	Quartile	All	0.118	0.563	<.001	21	view →
ACC	DFS	Median	All	0.270	0.695	.003	19	view →
LIHC	DFS	Tertile	All	0.353	0.479	.012	14	view →
KIRC	DFS	Tertile	All	0.866	0.754	.007	12	view →
SARC	OS	Tertile	All	0.640	0.846	.008	9	view →
DLBC	DFS	Tertile	IV	0.120	0.784	.045	6	view →
UCEC	DFS	Tertile	IV	0.912	0.529	.024	4	view →
LUAD	DFS	Median	II,III,IV	0.621	0.728	.032	4	view →
GBM	DFS	Median	All	0.361	0.210	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

WDR45BP1–KICH (DFS)

Open the KICH breakdown →