Q-omics provides the consensus-scored WDR45BP1 profile across patient tissues and cancer cell-line models. WDR45BP1 expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, WDR45BP1 is differentially expressed in 3, with the highest sampling consensus in COAD. Additionally, WDR45BP1 RNA expression shows 9,711 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KICH, COAD, and THYM as cancer lineages where WDR45BP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for WDR45BP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes WDR45BP1 survival associations across molecular data types. WDR45BP1 RNA expression shows survival associations in the most cancer types (19). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible WDR45BP1 RNA expression–survival associations across cancer types. High WDR45BP1 expression shows unfavorable associations in KICH, MESO, ACC and LIHC, but favorable associations in SKCM and BRCA. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify KICH as the clearest survival context for WDR45BP1 RNA expression.
This table summarizes WDR45BP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for WDR45BP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. WDR45BP1 shows higher tumor expression in COAD, LUAD and LIHC. The COAD box plot shows higher WDR45BP1 RNA expression in tumor versus normal tissue (log2 FC = +0.336, t-test p = .005).
This table shows molecular features associated with WDR45BP1 in patient tissues and cancer cell lines. In patient samples, WDR45BP1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
