Across TCGA pan-cancer cohorts, WDR45BP1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of WDR45BP1’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where WDR45BP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types WDR45BP1 is over-expressed in tumor.
COAD, LUAD, and LIHC are the cancer types where WDR45BP1 tumor–normal differential expression is most reproducible.