WDR41

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, WDR41 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,483 significant associations in total. BONE shows the largest number of these associations.

The most reproducible WDR41-associated GO terms across cancer lineages are Negative regulation of beige fat cell differentiation, Protein neddylation, and Interkinetic nuclear migration. Each is linked with WDR41 in more than 9 cancer types. Because this analysis shows association rather than direction, both WDR41-to-partner and partner-to-WDR41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of beige fat cell differentiation grouped by WDR41-low versus WDR41-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR41→partner) and Y-score (partner→WDR41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIVERNegative regulation of beige fat cell differentiation →+0.231+1.435<.001<.001310
LIVERProtein neddylation →+0.107+0.945<.001.00139
LARGE_INTESTINEInterkinetic nuclear migration →+0.072+1.002.001<.00139
LIVERNucleotide-excision repair →+0.080+1.076.002.006210
LARGE_INTESTINEProtein localization to cilium →+0.045+0.889.001<.00139
CNSRibosome disassembly →+0.054+0.417.001.00338
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,483 associations by consensus.

Negative regulation of beige fat cell differentiation by WDR41 expression — LIVER

Box plot of Negative regulation of beige fat cell differentiation in WDR41-low vs WDR41-high samples in LIVER.

Explore this box plot interactively →

Exploration