WDR41

Across TCGA pan-cancer cohorts, WDR41 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of WDR41’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where WDR41 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types WDR41 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

KIRC, LIHC, and COAD are the cancer types where WDR41 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in WDR41 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	IV	+0.870	<.001	12	view →
LIHC	Female	II,III,IV	+0.965	<.001	9	view →
COAD	All	II,III,IV	+0.413	<.001	9	view →
KIRP	All	II,III,IV	+0.627	.001	8	view →
HNSC	All	IV	+0.488	.001	7	view →
CHOL	All	All	+1.678	<.001	5	view →
READ	All	II,III,IV	+0.457	.002	3	view →
LUAD	Female	III,IV	−0.506	.016	2	view →
BRCA	All	II,III,IV	+0.153	.018	2	view →
THCA	All	IV	−0.435	.035	1	view →
KICH	All	All	−0.346	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

WDR41–KIRC

Open the KIRC breakdown →