WDR38

Across TCGA cell cohorts, WDR38 RNA expression is significantly associated with the go_rna of many other GO terms, with 965 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible WDR38-associated GO terms across cancer lineages are Negative regulation of ERBB signaling pathway, Protein-containing complex disassembly, and Photoreceptor cell maintenance. Each is linked with WDR38 in more than 5 cancer types. Because this analysis shows association rather than direction, both WDR38-to-partner and partner-to-WDR38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of ERBB signaling pathway grouped by WDR38-low versus WDR38-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR38→partner) and Y-score (partner→WDR38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of ERBB signaling pathway →	+0.062	+0.086	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Protein-containing complex disassembly →	+0.062	+0.120	.001	.002	3	5
URINARY_TRACT	Photoreceptor cell maintenance →	-0.084	-0.082	.004	.006	3	5
STOMACH	Regulation of pattern recognition receptor signaling pathway →	+0.061	+0.082	<.001	.002	3	5
SOFT_TISSUE	Regulation of T cell differentiation →	+0.046	+0.056	<.001	.003	3	5
KIDNEY	Positive regulation of mononuclear cell migration →	+0.100	+0.077	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 965 associations by consensus.

Negative regulation of ERBB signaling pathway by WDR38 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →