WDR38

Across TCGA pan-cancer cohorts, WDR38 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated WDR38 data layer compared with 4 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher WDR38 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated WDR38 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

KICH, HNSC, and BRCA are the cancer types where WDR38 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.601	1.000	<.001	79	view →
HNSC	DFS	Tertile	All	0.777	0.628	.004	65	view →
BRCA	DFS	Tertile	All	0.612	0.464	<.001	56	view →
LGG	OS	Median	All	0.346	0.516	<.001	51	view →
LIHC	OS	Tertile	All	0.400	0.639	<.001	45	view →
ACC	OS	Quartile	II,III,IV	0.252	0.749	<.001	40	view →
LUSC	DFS	Quartile	III,IV	0.723	0.396	.004	31	view →
SARC	OS	Tertile	All	0.849	0.591	<.001	26	view →
THYM	OS	Tertile	II,III,IV	0.446	1.000	.006	26	view →
READ	DFS	Median	IV	0.179	0.936	.010	21	view →
TGCT	DFS	Tertile	All	0.464	0.890	<.001	20	view →
UVM	OS	Tertile	All	0.824	0.422	.017	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

WDR38–KICH (DFS)

Open the KICH breakdown →