WDR38

Across TCGA cell cohorts, WDR38 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible WDR38-associated genes across cancer lineages are SMIM9, DEFB135, and CGB5. Each is linked with WDR38 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR38-to-partner and partner-to-WDR38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM9 grouped by WDR38-low versus WDR38-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR38→partner) and Y-score (partner→WDR38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SMIM9 →	+0.058	+4.977	<.001	.007	3	1
SKIN	DEFB135 →	+0.640	+5.415	<.001	.004	3	1
BLOOD_Leukemia	CGB5 →	+0.083	+4.409	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

SMIM9 by WDR38 expression — SKIN

Explore this box plot interactively →