WDR31

Across TCGA patient cohorts, WDR31 mutation is significantly associated with the RNA expression of many other genes, with 507 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR31-associated genes across cancer lineages are SCEL-AS1, RNU6-591P, and CIZ1. Each is linked with WDR31 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR31-to-partner and partner-to-WDR31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCEL-AS1 grouped by WDR31-low versus WDR31-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR31→partner) and Y-score (partner→WDR31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SCEL-AS1 →	+0.032	+3.265	.002	.006	3	3
PRAD	RNU6-591P →	+0.304	+7.939	<.001	.008	3	3
UCEC	CIZ1 →	+0.628	+3.212	.001	.009	3	2
HNSC	MIR455 →	+0.344	+3.685	.004	.009	3	2
UCEC	RNA5SP496 →	+0.738	+2.529	<.001	.003	3	2
HNSC	SNORA40C →	+0.327	+5.497	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 507 associations by consensus.

SCEL-AS1 by WDR31 expression — SKCM

Explore this box plot interactively →