Q-omics provides the consensus-scored MIR455 profile across patient tissues and cancer cell-line models. MIR455 expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, MIR455 is differentially expressed in 5, with the highest sampling consensus in KICH. Additionally, MIR455 RNA expression shows 7,579 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight COAD, KICH, and THYM as cancer lineages where MIR455 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR455 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR455 survival associations across molecular data types. MIR455 RNA expression shows survival associations in the most cancer types (19). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR455 RNA expression–survival associations across cancer types. High MIR455 expression shows unfavorable associations in COAD, MESO, TGCT, STAD, DLBC and SKCM. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for MIR455 RNA expression.
This table summarizes MIR455 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for MIR455. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR455 shows lower tumor expression in KICH and higher tumor expression in STAD, KIRP, COAD and KIRC. The KICH box plot shows higher MIR455 RNA expression in normal versus tumor tissue (log2 FC = −0.138, t-test p = .032).
This table shows molecular features associated with MIR455 in patient tissues and cancer cell lines. In patient samples, MIR455 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
