Across TCGA patient cohorts, WDR27 mutation is significantly associated with the RNA expression of many other genes, with 2,591 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR27-associated genes across cancer lineages are BSX, RN7SKP2, and IGLL4P. Each is linked with WDR27 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR27-to-partner and partner-to-WDR27 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR27→partner) and Y-score (partner→WDR27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	BSX →	+0.077	+4.534	.007	.005	3	2
LGG	RN7SKP2 →	+0.193	+5.632	<.001	.002	3	2
LGG	IGLL4P →	+0.206	+4.936	.001	.005	3	2
COAD	RNU6-854P →	+0.342	+3.061	.005	.002	3	2
COAD	MIR194-1 →	+0.664	+3.242	<.001	.001	3	2
COAD	TRGJP2 →	+0.879	+2.811	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,591 associations by consensus.

Exploration

WDR27 survival (RNA) · tumor vs normal (RNA) · all WDR27 data types