Across TCGA cell cohorts, WDR27 mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR27-associated genes across cancer lineages are TBC1D28, GHRH, and KRTAP17-1. Each is linked with WDR27 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR27-to-partner and partner-to-WDR27 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR27→partner) and Y-score (partner→WDR27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBC1D28 →	+0.083	+2.793	.003	.002	3	2
OESOPHAGUS	GHRH →	+0.060	+4.906	<.001	.006	3	1
SKIN	KRTAP17-1 →	+0.025	+4.977	<.001	.007	3	1
LUNG_SCLC	KRTAP9-7 →	+0.073	+5.643	<.001	.002	3	1
LUNG_SCLC	KRTAP9-6 →	+0.136	+5.643	<.001	.002	3	1
LARGE_INTESTINE	VPS4B →	+0.770	+3.082	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Exploration

WDR27 survival (RNA) · tumor vs normal (RNA) · all WDR27 data types