Across TCGA cell cohorts, WDR27 mutation is significantly associated with the mutation status of many other genes, with 4,308 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR27-associated genes across cancer lineages are ATP2C2, FKBP15, and ENOX1. Each is linked with WDR27 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR27-to-partner and partner-to-WDR27 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR27→partner) and Y-score (partner→WDR27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	ATP2C2 →	+5.297	+5.297	.004	.004	1	3
BREAST	FKBP15 →	+4.297	+4.857	.009	.009	1	3
BLOOD_Leukemia	ENOX1 →	+5.083	+3.672	.001	.001	1	3
BREAST	COL8A1 →	+4.297	+4.857	.009	.009	1	3
BLOOD_Leukemia	PBXIP1 →	+3.498	+3.260	.001	.001	1	3
LARGE_INTESTINE	THBS2 →	+3.222	+5.050	<.001	<.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,308 associations by consensus.

Exploration

WDR27 survival (RNA) · tumor vs normal (RNA) · all WDR27 data types