WDR12

Across TCGA cell cohorts, WDR12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,753 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WDR12-associated GO terms across cancer lineages are Ribosome assembly, Ribosomal large subunit assembly, and rRNA metabolic process. Each is linked with WDR12 in more than 19 cancer types. Because this analysis shows association rather than direction, both WDR12-to-partner and partner-to-WDR12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosome assembly grouped by WDR12-low versus WDR12-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR12→partner) and Y-score (partner→WDR12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Ribosome assembly →	+0.111	+1.081	<.001	.003	3	20
BONE	Ribosomal large subunit assembly →	+0.135	+1.136	<.001	<.001	3	19
PANCREAS	rRNA metabolic process →	+0.108	+1.007	<.001	<.001	3	17
LUNG_SCLC	Ribosomal small subunit biogenesis →	+0.111	+0.722	<.001	<.001	3	17
BONE	Maturation of 5.8S rRNA →	+0.137	+1.152	.002	.001	3	17
OVARY	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.097	+0.718	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,753 associations by consensus.

Ribosome assembly by WDR12 expression — BLOOD_Myeloma

Explore this box plot interactively →