WDR11

Across TCGA patient cohorts, WDR11 mutation is significantly associated with the RNA expression of many other genes, with 2,527 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR11-associated genes across cancer lineages are RN7SL248P, PCSK1N, and ATP1B2. Each is linked with WDR11 in more than 3 cancer types. Because this analysis shows association rather than direction, both WDR11-to-partner and partner-to-WDR11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by WDR11-low versus WDR11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR11→partner) and Y-score (partner→WDR11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.040	+2.552	<.001	.003	3	4
UCEC	PCSK1N →	-1.580	-2.190	<.001	<.001	3	3
UCEC	ATP1B2 →	-0.597	-2.796	.001	<.001	3	3
COAD	ZWINT →	+0.572	+3.026	<.001	<.001	3	3
COAD	SLC19A3 →	-1.080	-3.000	<.001	.001	3	3
SKCM	PDGFD →	-1.189	-3.800	.004	<.001	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,527 associations by consensus.

RN7SL248P by WDR11 expression — UCEC

Explore this box plot interactively →