WBP2NL

Across TCGA patient cohorts, WBP2NL mutation is significantly associated with the RNA expression of many other genes, with 2,514 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WBP2NL-associated genes across cancer lineages are MIR3943, RNU6-1139P, and USP17L3. Each is linked with WBP2NL in more than 1 cancer types. Because this analysis shows association rather than direction, both WBP2NL-to-partner and partner-to-WBP2NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3943 grouped by WBP2NL-low versus WBP2NL-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP2NL→partner) and Y-score (partner→WBP2NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR3943 →	+0.383	+7.640	<.001	.009	3	2
LUAD	RNU6-1139P →	+0.982	+7.930	<.001	.008	3	2
LUAD	USP17L3 →	+0.064	+7.930	<.001	.008	3	2
LUAD	MTCO2P6 →	+0.269	+7.930	<.001	.008	3	2
LUAD	MIR3938 →	+1.228	+7.930	<.001	.008	3	2
UCEC	ADRA2C →	-1.148	-2.311	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,514 associations by consensus.

MIR3943 by WBP2NL expression — BLCA

Explore this box plot interactively →