WBP2NL

Across TCGA pan-cancer cohorts, WBP2NL RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated WBP2NL data layer compared with 6 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher WBP2NL RNA is associated with better overall survival. In most high-consensus cancer types, elevated WBP2NL expression acts as an unfavorable survival marker, although some lineages such as BLCA and LUAD show a favorable association.

BLCA, LUAD, and LIHC are the cancer types where WBP2NL RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.710	0.514	<.001	90	view →
LUAD	OS	Quartile	II,III,IV	0.671	0.438	.001	90	view →
LIHC	DFS	Median	All	0.465	0.618	<.001	78	view →
ACC	DFS	Median	All	0.247	0.621	<.001	50	view →
PAAD	DFS	Median	All	0.504	0.220	<.001	50	view →
CESC	DFS	Median	All	0.814	0.665	.001	44	view →
UCS	DFS	Tertile	IV	0.871	0.237	.024	40	view →
BRCA	OS	Median	IV	0.645	0.176	.005	32	view →
KIRP	DFS	Quartile	All	0.491	0.638	.002	31	view →
KICH	DFS	Quartile	III,IV	0.189	0.913	.002	29	view →
SKCM	OS	Median	All	0.395	0.285	.008	22	view →
UVM	DFS	Quartile	III,IV	0.184	0.736	.007	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

WBP2NL–BLCA (OS)

Open the BLCA breakdown →