WBP2NL

Across TCGA cell cohorts, WBP2NL RNA expression is significantly associated with the go_rna of many other GO terms, with 2,503 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible WBP2NL-associated GO terms across cancer lineages are Fertilization, Flagellated sperm motility, and Sperm motility. Each is linked with WBP2NL in more than 9 cancer types. Because this analysis shows association rather than direction, both WBP2NL-to-partner and partner-to-WBP2NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fertilization grouped by WBP2NL-low versus WBP2NL-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP2NL→partner) and Y-score (partner→WBP2NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Fertilization →	-0.101	-0.767	<.001	<.001	3	10
SKIN	Flagellated sperm motility →	-0.055	-0.279	.001	.002	2	9
SKIN	Sperm motility →	-0.055	-0.279	.001	.002	2	9
SKIN	Cilium movement involved in cell motility →	-0.063	-0.357	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.090	+0.660	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.100	+0.707	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,503 associations by consensus.

Fertilization by WBP2NL expression — OVARY

Explore this box plot interactively →