WBP1L

Across TCGA patient cohorts, WBP1L mutation is significantly associated with the RNA expression of many other genes, with 2,401 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WBP1L-associated genes across cancer lineages are HNRNPMP2, RNU6-258P, and RNU7-147P. Each is linked with WBP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both WBP1L-to-partner and partner-to-WBP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNRNPMP2 grouped by WBP1L-low versus WBP1L-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP1L→partner) and Y-score (partner→WBP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	HNRNPMP2 →	+0.073	+6.342	<.001	.001	3	2
STAD	RNU6-258P →	+0.479	+4.184	.001	.009	3	2
STAD	RNU7-147P →	+1.154	+4.691	<.001	.003	3	2
STAD	RNU6-871P →	+0.853	+4.290	<.001	.008	3	2
UCEC	ZNF25-DT →	+0.111	+1.858	.004	.004	3	2
SKCM	MTCO1P43 →	+0.090	+4.743	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,401 associations by consensus.

HNRNPMP2 by WBP1L expression — CESC

Explore this box plot interactively →