WASHC1

Across TCGA patient cohorts, WASHC1 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WASHC1-associated genes across cancer lineages are POTED, NTAN1P1, and MIR6766. Each is linked with WASHC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both WASHC1-to-partner and partner-to-WASHC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POTED grouped by WASHC1-low versus WASHC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASHC1→partner) and Y-score (partner→WASHC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POTED →	+0.034	+5.852	<.001	.003	3	1
UCEC	NTAN1P1 →	+0.209	+5.937	.002	.002	3	1
UCEC	MIR6766 →	+0.943	+5.358	<.001	.006	3	1
UCEC	MIR6857 →	+0.626	+5.358	.001	.006	3	1
UCEC	MIR218-1 →	+0.739	+4.982	<.001	.009	3	1
UCEC	IGHD1-26 →	+1.914	+5.484	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

POTED by WASHC1 expression — UCEC

Explore this box plot interactively →