WASHC1

Across TCGA pan-cancer cohorts, WASHC1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of WASHC1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where WASHC1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types WASHC1 is over-expressed in tumor, although a few such as UCEC and LUAD show the opposite, repressed pattern.

LIHC, HNSC, and STAD are the cancer types where WASHC1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in WASHC1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	+1.177	<.001	9	view →
HNSC	All	All	+0.335	.014	6	view →
STAD	All	II,III,IV	+0.589	.012	3	view →
CHOL	Male	All	+1.763	<.001	2	view →
UCEC	All	III,IV	−0.477	.049	2	view →
KIRP	All	IV	+0.469	.045	2	view →
ESCA	All	All	+0.466	.028	2	view →
LUAD	All	All	−0.216	.024	2	view →
COAD	All	IV	+0.644	.049	1	view →
KICH	Male	IV	+0.610	.013	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

WASHC1–LIHC

Open the LIHC breakdown →