WASH4P

Across TCGA patient cohorts, WASH4P RNA expression is significantly associated with the go_rna of many other GO terms, with 7,158 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible WASH4P-associated GO terms across cancer lineages are Regulation of actin nucleation, Regulation of Arp2/3 complex-mediated actin nucleation, and Regulation of DNA strand elongation. Each is linked with WASH4P in more than 25 cancer types. Because this analysis shows association rather than direction, both WASH4P-to-partner and partner-to-WASH4P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actin nucleation grouped by WASH4P-low versus WASH4P-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WASH4P→partner) and Y-score (partner→WASH4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Regulation of actin nucleation →	+0.040	+0.352	<.001	.002	1	26
LAML	Regulation of Arp2/3 complex-mediated actin nucleation →	+0.046	+0.339	<.001	.002	1	26
KIRP	Regulation of DNA strand elongation →	+0.035	+0.455	<.001	<.001	3	23
CHOL	Regulation of telomere maintenance in response to DNA damage →	+0.044	+0.553	<.001	.002	3	23
ESCA	Positive regulation of double-strand break repair →	+0.041	+0.192	<.001	<.001	3	22
ACC	Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' →	+0.060	+0.684	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,158 associations by consensus.

Regulation of actin nucleation by WASH4P expression — LAML

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