WASH4P

Across TCGA pan-cancer cohorts, WASH4P RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of WASH4P’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where WASH4P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types WASH4P is over-expressed in tumor, although a few such as PRAD show the opposite, repressed pattern.

LIHC, HNSC, and CHOL are the cancer types where WASH4P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in WASH4P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	+0.702	<.001	9	view →
HNSC	All	All	+0.202	<.001	6	view →
CHOL	Male	All	+1.296	<.001	5	view →
BLCA	All	All	+0.273	.030	3	view →
ESCA	All	II,III,IV	+0.260	.003	2	view →
LUSC	All	All	+0.215	.013	2	view →
PRAD	All	All	−0.099	.047	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

WASH4P–LIHC

Open the LIHC breakdown →