WASH4P

Across TCGA cell cohorts, WASH4P mutation is significantly associated with the mutation status of many other genes, with 727 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WASH4P-associated genes across cancer lineages are ZNF641, ADGRG6, and ST14. Each is linked with WASH4P in more than 2 cancer types. Because this analysis shows association rather than direction, both WASH4P-to-partner and partner-to-WASH4P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF641 grouped by WASH4P-low versus WASH4P-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASH4P→partner) and Y-score (partner→WASH4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	ZNF641 →	+5.392	+5.392	.004	.004	1	3
BREAST	ADGRG6 →	+4.297	+4.857	.009	.009	1	3
BLOOD_Leukemia	ST14 →	+4.000	+5.050	.008	.008	1	3
BLOOD_Leukemia	ANO4 →	+4.321	+5.285	.005	.005	1	3
PANCREAS	FARP1 →	+5.115	+5.115	.005	.005	1	2
PANCREAS	TRIM46 →	+5.115	+5.115	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 727 associations by consensus.

ZNF641 by WASH4P expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →