WASF3

Across TCGA cell cohorts, WASF3 mutation is significantly associated with the RNA expression of many other genes, with 746 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WASF3-associated genes across cancer lineages are RNF125, MED31, and AKAP3. Each is linked with WASF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both WASF3-to-partner and partner-to-WASF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNF125 grouped by WASF3-low versus WASF3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASF3→partner) and Y-score (partner→WASF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RNF125 →	+0.868	+2.158	<.001	.004	3	2
LARGE_INTESTINE	MED31 →	+0.656	+3.321	<.001	.003	3	2
LARGE_INTESTINE	AKAP3 →	+0.723	+3.257	<.001	.002	3	2
LARGE_INTESTINE	ZBED3 →	+0.881	+2.850	<.001	<.001	3	2
LARGE_INTESTINE	KLHL8 →	+0.596	+2.850	.001	<.001	3	2
LARGE_INTESTINE	RNF145 →	+0.622	+2.158	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 746 associations by consensus.

RNF125 by WASF3 expression — LARGE_INTESTINE

Explore this box plot interactively →