WASF2

Across TCGA patient cohorts, WASF2 mutation is significantly associated with the RNA expression of many other genes, with 4,204 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WASF2-associated genes across cancer lineages are EIF4EBP2P3, USP12PY, and H2AB2. Each is linked with WASF2 in more than 2 cancer types. Because this analysis shows association rather than direction, both WASF2-to-partner and partner-to-WASF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF4EBP2P3 grouped by WASF2-low versus WASF2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASF2→partner) and Y-score (partner→WASF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EIF4EBP2P3 →	+0.156	+6.268	<.001	.001	3	3
CESC	USP12PY →	+0.030	+4.103	<.001	.002	3	3
BRCA	H2AB2 →	+0.089	+8.057	<.001	.005	3	2
SKCM	SNORA84 →	+0.519	+4.164	<.001	<.001	3	2
CESC	HPRT1P2 →	+0.041	+5.584	<.001	.001	3	2
BLCA	MIR3928 →	+0.510	+3.479	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,204 associations by consensus.

EIF4EBP2P3 by WASF2 expression — BRCA

Explore this box plot interactively →