WASF1

Across TCGA patient cohorts, WASF1 mutation is significantly associated with the RNA expression of many other genes, with 672 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WASF1-associated genes across cancer lineages are RN7SL159P, OR4V1P, and LINC02287. Each is linked with WASF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both WASF1-to-partner and partner-to-WASF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL159P grouped by WASF1-low versus WASF1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASF1→partner) and Y-score (partner→WASF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RN7SL159P →	+0.192	+4.756	.004	<.001	3	2
SKCM	OR4V1P →	+0.021	+4.302	<.001	.007	3	2
SKCM	LINC02287 →	+0.127	+3.896	.005	.002	3	2
SKCM	MIR5585 →	+0.467	+3.099	<.001	.007	3	2
COAD	SNORA10B →	+0.560	+4.693	<.001	.007	3	2
LUSC	RNU6-627P →	+1.086	+5.081	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 672 associations by consensus.

RN7SL159P by WASF1 expression — STAD

Explore this box plot interactively →