WASF1

Across TCGA pan-cancer cohorts, WASF1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated WASF1 data layer compared with 4 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher WASF1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated WASF1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LGG show a favorable association.

LIHC, MESO, and KIRP are the cancer types where WASF1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.705	0.845	<.001	91	view →
MESO	DFS	Tertile	All	0.278	0.530	.001	87	view →
KIRP	DFS	Median	All	0.787	0.919	<.001	79	view →
KIRC	DFS	Median	All	0.761	0.493	<.001	52	view →
LGG	DFS	Median	All	0.475	0.306	<.001	44	view →
HNSC	OS	Median	All	0.492	0.703	.002	39	view →
ACC	DFS	Tertile	All	0.376	0.785	.004	32	view →
UCS	OS	Median	III,IV	0.578	0.179	.004	32	view →
COAD	DFS	Quartile	All	0.366	0.616	.001	27	view →
STAD	OS	Tertile	All	0.415	0.654	.006	25	view →
LUSC	OS	Tertile	All	0.813	0.710	.012	22	view →
GBM	DFS	Median	All	0.385	0.184	.005	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

WASF1–LIHC (OS)

Open the LIHC breakdown →