WASF1

Across TCGA cell cohorts, WASF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,256 significant associations in total. BONE shows the largest number of these associations.

The most reproducible WASF1-associated GO terms across cancer lineages are Regulation of termination of RNA polymerase II transcription, Regulation of termination of RNA polymerase II transcription, poly(A)-coupled, and Regulation of termination of DNA-templated transcription. Each is linked with WASF1 in more than 15 cancer types. Because this analysis shows association rather than direction, both WASF1-to-partner and partner-to-WASF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of termination of RNA polymerase II transcription grouped by WASF1-low versus WASF1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WASF1→partner) and Y-score (partner→WASF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of termination of RNA polymerase II transcription →	+0.183	+2.327	<.001	<.001	3	16
STOMACH	Regulation of termination of RNA polymerase II transcription, poly(A)-coupled →	+0.188	+2.463	<.001	<.001	3	16
STOMACH	Regulation of termination of DNA-templated transcription →	+0.183	+2.327	<.001	<.001	3	16
SOFT_TISSUE	Regulation of neurotrophin TRK receptor signaling pathway →	+0.264	+1.477	<.001	<.001	3	16
OESOPHAGUS	Lamellipodium morphogenesis →	+0.174	+1.411	<.001	<.001	3	15
BONE	Protein import into nucleus →	+0.062	+1.590	.003	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,256 associations by consensus.

Regulation of termination of RNA polymerase II transcription by WASF1 expression — STOMACH

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