WASF1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, WASF1 protein abundance is significantly associated with the go_rna of many other GO terms, with 2,077 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WASF1-associated GO terms across cancer lineages are Myelin maintenance, N-acetylneuraminate biosynthetic process, and Pentose catabolic process. Each is linked with WASF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both WASF1-to-partner and partner-to-WASF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myelin maintenance grouped by WASF1-low versus WASF1-high in STOMACH.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WASF1→partner) and Y-score (partner→WASF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHMyelin maintenance →-0.221-0.474.001.00135
LARGE_INTESTINEN-acetylneuraminate biosynthetic process →-0.156-0.498.007<.00135
SKINPentose catabolic process →+0.115+0.418.003.00435
CNSIntegrin-mediated signaling pathway →-0.176-0.672.002.00335
BONERegulation of very-low-density lipoprotein particle clearance →-0.313-0.511.002.00134
BONENegative regulation of very-low-density lipoprotein particle clearance →-0.313-0.511.002.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,077 associations by consensus.

Myelin maintenance by WASF1 expression — STOMACH

Box plot of Myelin maintenance in WASF1-low vs WASF1-high samples in STOMACH.

Explore this box plot interactively →

Exploration