WAC

Across TCGA patient cohorts, WAC protein abundance is significantly associated with the RNA expression of many other genes, with 9,971 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible WAC-associated genes across cancer lineages are SUV39H2, NUDT5, and MTPAP. Each is linked with WAC in more than 6 cancer types. Because this analysis shows association rather than direction, both WAC-to-partner and partner-to-WAC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WAC versus SUV39H2 in GBM, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WAC→partner) and Y-score (partner→WAC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SUV39H2 →	+0.738	+0.326	<.001	<.001	3	7
HNSC	NUDT5 →	+0.681	+0.161	.001	<.001	3	6
UCEC	MTPAP →	+0.570	+0.243	<.001	<.001	3	6
HNSC	CUL2 →	+0.895	+0.207	.002	<.001	3	6
LUAD	MASTL →	+0.653	+0.244	<.001	<.001	3	6
UCEC	RPP38 →	+0.695	+0.238	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,971 associations by consensus.

WAC vs SUV39H2 — GBM

Explore this scatter interactively →